Integrated granulation line for pharmaceutical tablet manufacturing
Wet granulation involves multiple unit operations that must be tightly controlled and connected to ensure consistent product quality, reproducible batch performance, and efficient production throughput.
Integrate granulation drying milling and blending into one continuous process
The Gansons Integrated Granulation Line is a complete wet granulation solution that connects all critical processing steps into a single coordinated system. The line typically includes a high shear mixer granulator, inline wet mill, fluid bed dryer, dry milling system, and IBC blender, enabling controlled material flow from raw powder to final blend.
Each process step is engineered to work in balance with the others, creating a continuous manufacturing sequence with predictable throughput and minimal manual intervention. Closed material transfer between units reduces handling, limits operator exposure, and improves process reliability.
The system is controlled through a centralized automation platform that manages process parameters across all units. This ensures consistent batch reproducibility, supports recipe-driven operation, and enables compliance with pharmaceutical data integrity requirements such as 21 CFR Part 11.
The integrated design reduces downtime through synchronized equipment operation, fast changeovers, and clean-in-place functionality. The line can be configured for different batch sizes and scaled from development to full production, maintaining consistent process performance across capacities.
The equipment is designed for pharmaceutical environments, with high-containment options, ATEX-compliant configurations, and construction materials suitable for regulated production.
Benefits
- — Integrated processing from granulation to final blending
- — Consistent throughput through line-balanced system design
- — Reduced manual handling with closed material transfer
- — Centralized automation for reproducible batch control
- — Scalable from R&D to full production